NEET Human Health and Disease PYQs & Practice Questions

10 free NEET Biology questions on Human Health and Disease, starting with previous year questions (2016–2026). Tap “Show answer” to check each one. No login needed.

Topics: WHO Definition of Health · Definition of a Pathogen · Diagnostic Test for Typhoid · Classifying Diseases as Infectious or Non-infectious · Genes Responsible for Cancer · Spread of Malignant Tumour Cells · Modes of HIV Transmission · Cellular Protection Against Viral Infection · Component of Tobacco Stimulating Adrenaline Secretion · Composition of Antivenom · Age-Related Involution of a Gland · Diseases and Diagnostic Tests

1. Q1NEET 2026Clot Busters - Thrombolytic Agents

   Which of the following is used as a clot buster?

   • A. Penicillin
   • B. Cyclosporin A
   • C. Statins
   • D. Streptokinase
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   Answer: C — Statins

   Streptokinase, produced by the bacterium Streptococcus, is used as a clot buster (thrombolytic agent) to dissolve blood clots in conditions like heart attacks.

2. Q2NEET 2026Primary vs Secondary Lymphoid Organs

   Which of the following are secondary lymphoid organs? (a) Bone marrow (b) Tonsils (c) Spleen (d) Thymus Choose the correct answer from the options given below:

   • A. (b) and (c) only
   • B. (b) and (d) only
   • C. (a) and (d) only
   • D. (a) and (b) only
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   Answer: —

   Bone marrow and thymus are PRIMARY lymphoid organs (where lymphocytes mature). Tonsils and spleen are SECONDARY lymphoid organs (where mature lymphocytes interact with antigens and undergo proliferation into effector cells), along with lymph nodes, Peyer's patches, and appendix. So (b) and (c) only.

3. Q3NEET 2026Sexually Transmitted Diseases

   Which of the following disease is not sexually transmitted?

   • A. Tuberculosis
   • B. Gonorrhoea
   • C. Genital warts
   • D. Syphilis
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   Answer: —

   Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis and is not sexually transmitted. Gonorrhoea, genital warts, and syphilis are all sexually transmitted diseases (STDs/STIs).

4. Q4NEET 2026Immunoglobulins in Colostrum

   Colostrum, secreted by mother during initial days of lactation, is abundant in________.

   • A. IgM
   • B. IgA
   • C. IgD
   • D. IgG
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   Answer: A — IgM

   Colostrum, the first milk secreted during initial days of lactation, is rich in IgA antibodies, which help protect the newborn infant against infections.

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5. Q5NEET 2025Cancer Detection and Treatment

   Which are correct: A. Computed tomography and magnetic resonance imaging detect cancers of internal organs. B. Chemotherapeutics drugs are used to kill non-cancerous cells. C. α-interferon activate the cancer patients' immune system and helps in destroying the tumour. D. Chemotherapeutic drugs are biological response modifiers. E. In the case of leukaemia blood cell counts are decreased. Choose the correct answer from the options given below:

   • A. B and D only
   • B. D and E only
   • C. C and D only
   • D. A and C only
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   Answer: C — C and D only

   A is correct: CT scan (X-ray based) and MRI (magnetic resonance based) detect cancers of internal organs. C is correct: α-interferons activate the immune system to kill cancerous cells, effective especially for Kaposi's sarcoma. B is incorrect (chemo drugs kill cancerous, not non-cancerous, cells). D is incorrect (chemo drugs are not biological response modifiers — interferons are). E is incorrect (leukemia increases WBC count). So A and C only.

6. Q6NEET 2025Antibody Structure (Statement NOT Correct)

   Identify the statement that is NOT correct.

   • A. Each antibody has two light and two heavy chains.
   • B. The heavy and light chains are held together by disulfide bonds.
   • C. Antigen binding site is located at C-terminal region of antibody molecules.
   • D. Constant region of heavy and light chains are located at C-terminus of antibody molecules.
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   Answer: B — The heavy and light chains are held together by disulfide bonds.

   Each antibody monomer has 4 polypeptide chains (2 heavy, 2 light) held together by disulfide bonds. All chains have N- and C-termini. The antigen-binding site (paratope) is formed by the N-terminus of one heavy and one light chain, not the C-terminal region. The C-termini of both heavy chains form the constant regions. So statement (3) is NOT correct. Figure Class 12th NCERT Page No 74.

7. Q7NEET 2025Primary vs Secondary Lymphoid Organs

   After maturation, in primary lymphoid organs, the lymphocytes migrate for interaction with antigens to secondary lymphoid organs(s)/tissue(s) like: A. Thymus B. Bone marrow C. Spleen D. lymph nodes E. Peyer's patches Choose the correct answer from the options given below:

   • A. B, C, D only
   • B. A, B, C only
   • C. E, A, B only
   • D. C, D, E only
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   Answer: C — E, A, B only

   B and T lymphocytes are produced and differentiated in primary lymphoid organs (bone marrow and thymus), but after maturation they migrate to secondary lymphoid organs/tissues - spleen, lymph nodes, tonsils, and Peyer's patches (MALT) - where they interact with antigens to produce immune responses. So C, D, E only. Class 12th NCERT Page No. 138.

8. Q8NEET 2025Innate Immunity - Non-specific Defence Present at Birth

   Which of the following type of immunity is present at the time of birth and is a non-specific type of defence in the human body?

   • A. Acquired Immunity
   • B. Innate Immunity
   • C. Cell-mediated Immunity
   • D. Humoral Immunity
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   Answer: A — Acquired Immunity

   Innate immunity is non-specific and present in the body by birth, in the form of physical, physiological, cellular and cytokine barriers. Acquired immunity (antibody-based) is highly specific and develops through antigenic stimulation. Class 12th NCERT Page No. 134.

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9. Q9NEET 2024Diseases and Diagnostic Tests

   Match List I with List II. List I: (A) Common cold (B) Haemozoin (C) Widal test (D) Allergy List II: (I) Plasmodium (II) Typhoid (III) Rhinoviruses (IV) Dust mites Choose the correct answer from the options given below:

   • A. A-III, B-I, C-II, D-IV
   • B. A-IV, B-II, C-III, D-I
   • C. A-II, B-IV, C-III, D-I
   • D. A-I, B-III, C-II, D-IV
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   Answer: —

   Common cold is caused by Rhinoviruses (A-III). Haemozoin is a pigment produced by Plasmodium (B-I). Widal test is used to diagnose Typhoid (C-II). Dust mites are a common cause of allergy (D-IV). So A-III, B-I, C-II, D-IV is correct.

10. Q10NEET 2024Autoimmune Disorders

    Which of the following are Autoimmune disorders? A. Myasthenia gravis B. Rheumatoid arthritis C. Gout D. Muscular dystrophy E. Systemic Lupus Erythematosus (SLE) Choose the most appropriate answer from the options given below:

    • A. B, C & E only
    • B. C, D & E only
    • C. A, B & D only
    • D. A, B & E only
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    Answer: C — A, B & D only

    Myasthenia gravis, Rheumatoid arthritis, and Systemic Lupus Erythematosus (SLE) are all autoimmune disorders where the immune system attacks the body's own tissues. Gout is a metabolic disorder caused by uric acid crystal deposition, and Muscular dystrophy is a genetic disorder, neither of which is autoimmune.